Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQRLEVYKNYQRLYDLRIAILLNLSTLYLYNQDKNMCKQICYTLLEDAKNKKSYDR-------LAICYVRIGICTDDSKLIQKGSPFWS 3GW4 Chain:B ((105-176)) --------------LAASANAYEVATVALHFGDLAGARQEYEKSLVYAQQADDQVAIACAFRGLGDLAQQEKNLLEAQQHWLRARD---

General information: TITO was launched using: RESULT: Template: 3GW4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 224 -12115 -54.08 -186.38 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain B : 0.53 3D Compatibility (PKB) : -54.08 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.53 QMean score : 0.251

(partial model without unconserved sides chains): PDB file : Tito_3GW4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3GW4-query.scw PDB file : Tito_Scwrl_3GW4.pdb: