Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKLEVKDNKKLVLKSVICKKLHDTKVED-VDQEINRFHQHLQLLKAQIFGPLIVKSCGTTIH-DDGLITTDFEFYIQAHNAQQ---YSNIYDVQDSISVPYCLYVRFEDSPEYLQYAYSKLD-LYVYENDIQTDG-IVYTVYVNSS--PEKMVVDIFIPIVSL 1JYH Chain:A ((6-154)) ---------KQEEKRTVAGFHLV-GPWEQTVKKGFEQLMMWVDSKNIVP-KEWVAVYYDNPDETP--AEKLRCDTVVTVPGYFTLPENSEGVILTEITG-GQYAVAVARVVGDDFAKPWYQFFNSLLQDSAYEMLPKPCFEVYLNNGAEDGYWDIEMYVAVQP-

General information: TITO was launched using: RESULT: Template: 1JYH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 504 -16149 -32.04 -115.35 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -32.04 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.450

(partial model without unconserved sides chains): PDB file : Tito_1JYH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JYH-query.scw PDB file : Tito_Scwrl_1JYH.pdb: