Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFTCFIIHRTTIP---YFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHED-------SQFKGDHYVECYAVLDNT-------VIARDRITVPIDPLCGKDFIE------ 2HJQ Chain:A ((1-111)) MFTAKLIKGKTYNVMGITFRAGVSQTVPKKLYEYLNEN--PYFILTQELNNQKDDPINYTESELKGMNKAEHESIISNLGRNPSDFKNADERIAYILKQIDNKGELEHHHHHH

General information: TITO was launched using: RESULT: Template: 2HJQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 251 -1359 -5.41 -15.44 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -5.41 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.262

(partial model without unconserved sides chains): PDB file : Tito_2HJQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2HJQ-query.scw PDB file : Tito_Scwrl_2HJQ.pdb: