Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFEQDFITILGGNGAGKSTLFNTIAGTISLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTVAENLLIA-KFRGEKRGLFPRRLASYKDKFQATIEKVGNGLEKHLNTPIEFLSGGQRQALSLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKYGNRLIVMKEGRVIQDLKQEEKAKMKISDYYQLFE 3FH6 Chain:A ((2-214)) --ASVQLQNVTKAWG-----EVVVSKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLETITSGDLFIGEKRMNDTPPAERG--VGMVFQ--SYALYPHLSVAENMSFGLKLAGAKKEVINQRVNQVAEVLQ---------LAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQ--------------------

General information: TITO was launched using: RESULT: Template: 3FH6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1024 -66920 -65.35 -315.66 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -65.35 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.455

(partial model without unconserved sides chains): PDB file : Tito_3FH6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3FH6-query.scw PDB file : Tito_Scwrl_3FH6.pdb: