Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKLLREARQELAQLLRTKPQHIFFTSGGTEANNTTI--IGYCLRHQE--QGK---HIITTAIEHHAVLETIDYLVQHFGFEATIIQPE--NQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEIGQILK---QHPAA-------YHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSM----DFDSYLHGGDQEQKKRAGTENLPAIVGMVAA---LKENLEKQEEHFQHVQN-LETAFLAELEGIQYYLNR---GKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMYGANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG 3A9Z Chain:A ((20-425)) -VYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVAGRKAKDIINTARASLAKMIGGKPQDIIFTSGGTESNNLVIHSTVRCFHEQQTLQ--TRPHFITCTVEHDSIRLPLEHLVEDQVAEVTFVPVSKVNGQVEVEDILAAVRPTTCLVTIMLANNETGVIMPISEISRRIKALNQIRAASGLPRVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPR-IGALYVRGVGKLTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAEF-GKRIHLNSRFPGVERLPNTCNFSIQGSQLRGYMVLAQCQTLLASVGASCHSDHEDRPSPVLLSCGIPVDVARNAVRLSVGRSTTRAEVDLIVQDLKQAV--

General information: TITO was launched using: RESULT: Template: 3A9Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2009 -12655 -6.30 -34.77 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : -6.30 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.445

(partial model without unconserved sides chains): PDB file : Tito_3A9Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3A9Z-query.scw PDB file : Tito_Scwrl_3A9Z.pdb: