Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNHVASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVALGGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQPDGVLIDPLVLETLGKRELIEGMGEVIKYGLI------EDPELW----ALLTGLNGSVESILEHAETLIEHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISKIAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVPELGSATIHPV-------SLEEMKDYLVK 1XAH Chain:A ((1-352)) MKLQTTYPSNNYPIYVEHGAIKYIGTYLNQFDQS---FLLIDEYVNQYFANKFD----N----VHKVIIPAGEKTKTFEQYQETLEYILSHHVTRNTAIIAVGGGATGDFAGFVAATLLRGVHFIQVPTTILAH-DSSVGGKVGINSKQGKNLIGAFYRPTAVIYDLDFLKTLPFKQILSGYAEVYKHALLNGESATQDIEQHFKDREILQSLNGMDKYIAKGIET--------KLDIVVADEKEQGVRKFLNLGHTFGHAVEY---YHKIPHGHAVMVGIIYQFIVANALFDSKHDISHYIQYLIQ-LGYPLD----------------------GVQMVLMRQFGDIVVQHVDQLTLQHACEQLKTY---

General information: TITO was launched using: RESULT: Template: 1XAH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1645 -155666 -94.63 -508.71 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -94.63 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.503

(partial model without unconserved sides chains): PDB file : Tito_1XAH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XAH-query.scw PDB file : Tito_Scwrl_1XAH.pdb: