Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKRRRREITKMKRWIA-LSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTPGELANFMRDYLISMTAFSMMSTAIFSFPVVLHTDKINNWQKTLRHSPVNMVEYYLSKITSMLVDYLVSILVVFSVGHFVRGVDMSLGNWIGAALLLIVGSIAFVALGLTLTLLPTSQLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELLKTFLNEGGINLSATVYLLVFSVVLFGLTIYLQGHKENA 1L9G Chain:A ((1-191)) MYTREELMEIVSERVKKCTACPLHLNRTNVVV---GEGNLDTRIVFVG----EGPGEEEDKTGRPFVG-RAGMLLTELLRESGIRREDVYICNVVKCRPPNNRTPTPEEQAACGHFLLAQIEII---------------------NPDVIVALGATALSFF----VDGKKVSITKVRGNPIDW----LGGKKVIPTFHPSYLLRNRSNELRRIVLEDIEKAKSFIKKE----------------------------

General information: TITO was launched using: RESULT: Template: 1L9G.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 969 -67945 -70.12 -357.60 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.54 3D Compatibility (PKB) : -70.12 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.54 QMean score : 0.294

(partial model without unconserved sides chains): PDB file : Tito_1L9G.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1L9G-query.scw PDB file : Tito_Scwrl_1L9G.pdb: