Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVMLSLSVFFKGLGIGSGLIVAIGAQNAFVLKQGLKQQYVFWLCLICALSDSI-LIACGVLGFAEIMTASPILITVAKYLGATFLFVYGAKAFYAAFKTNQGM-ELDSSQKQTLTQALITCLAFTWLN------------PHVYLDTIVLI---------GSVATQLE------DKISFALGSILASWIFFFSLGYGARFLKPLFI-NPKAWKILDFM----IGCVMWSI-------AISLLI---------------- 3W6S Chain:A ((19-243)) ---------------------SIEWKLTANLRNGPTFFQ--------PLADSIEPLQFKLIGSDTVATAFPVF--DTKYIPDS-LINYLFKLFNLEIESGKTYPQLHSLTKQGFLNYWFHSFAVVVLQTDEKFIQDNQDWNSVLLGTFYIKPNYAPRCSHNCNAGFLVNGAHRGQKVGYRLAQVYLNWAPLL--GYKYSIFNLVFVTNQASWKIWDKLNFQRIGLVPHAGILNGFSEPVDAIIYGKDLTKIEPEFLSME

General information: TITO was launched using: RESULT: Template: 3W6S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 788 -58647 -74.42 -349.09 target 2D structure prediction score : 0.35 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -74.42 2D Compatibility (Sec. Struct. Predict.) : 0.35 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.271

(partial model without unconserved sides chains): PDB file : Tito_3W6S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3W6S-query.scw PDB file : Tito_Scwrl_3W6S.pdb: