Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNQKFKLPLAIAIASAVLVGCSSNKVKEAKPNPLPKLTESNKSLVPVFSRSVSSTNKADPLRLQLDASEGVVFTLDP-KGEVAAY-R--GKQRLWEKKVSKLG----LS------SGVEA--A----EGIVVVGNSKGQLFALDQATGEQKWTAQLSG-----ALLSPSLVQSGRVITIAN------DGTVFAHDVSSGQQVWAYKLPNVQFSL------------------------------R---GQPSPVS-LDPRTVLIASANA----------------YVYAIDTISGIPHFQRRVAVSEGRSDIQRLIDIDGDPV------VAG---QLMVTTSFQGQVTVTDLASQRVVWSEDSSS---------------T--------------------------KRPEVY--DNKVFVSST---------------------------------------DGKLTAYDLTTGEQLWQNDSLLNRHLSNPVVLGSDLIVGDLDGVLHLIDPTTGKLIGRSKTSGEVNTLRVIEKQLYVSTRKGDLSIWQNR 1W6S Chain:C ((38-514)) -----------------------------------------KQLRPAWTFSTGLLN---GHEGAPLVVDGKMYIHTSFPNNTFALGLDDPGTILWQDKPKQNPAARAVACCDLVNRGLAYWPGDGKTPALILKTQLDGNVAALNAETGETVWKVENSDIKVGSTLTIAPYVVKDKVIIGSSGAELGVRGYLTAYDVKTGEQVWRAYATGPDKDLLLASDFNIKNPHYGQKGLGTGTWEGDAWKIGGGTNWGWYAYDPGTNLIYFGTGNPAPWNETMRPGDNKWTMTIFGRDADTGEAKFGYQKTPHDEW-----DYAGVNVMMLSEQKDKDGKARKLLTHPDRNGIVYTLDRTDGALVSANKLDDTVNVFKSVDLKTGQPVRDPEYGTRMDHLAKDICPSAMGYHNQGHDSYDPKRELFFMGINHICMDWEPFMLPYKAGQFFVGATLNMYPGPKGDRQNYEGLGQIKAYNAITGDYKWEKMERFAVWGGTMATAGDLVFYGTLDGYLKARDSDTGDLLWKFKIPS---------------------------

General information: TITO was launched using: RESULT: Template: 1W6S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1699 61302 36.08 200.99 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain C : 0.63 3D Compatibility (PKB) : 36.08 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.459

(partial model without unconserved sides chains): PDB file : Tito_1W6S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1W6S-query.scw PDB file : Tito_Scwrl_1W6S.pdb: