Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSVVDFSQLPPPNLIKELDFEQILAKRKERFISLFPTEQQLQWKEVLERESEPVTKLLEENAYMELILTNQINQDARALLLAFSSGSDLDHIAISYYGLKRLVITPANPNTVPPTAAVMETDENLKERCILSLSGLNTAGATNAYKFFAK-S-ADGRVADASIISHEDNPCFLDVYITQHDSTNYEASPDLINIVQKALDPEDVRPVGDRPTVHSSKAVPYQIQARLYISQTAE---NVMLLSVAKKRLEKYVENS-KKIGQSIRRSAIYAALH-VDGVSRVEILNLTSDIEISRSQHAFCTSLDIQIGGTE 3H2T Chain:B ((342-474)) ---------------------------------------------------------------------------------------------------------------------------------------------ATDYDTFVSERFGSI-IQAVQTFTDSTKPGYAFIAAKPKS-G-LYLTTVQREDIKNYL--KDYNLAPITPSIISPNYLFIKTNLKVTYALNKLQESEQWLEGQIIDKIDRYYTEDVEIFNSSFAKSKMLTYVDDADHS---------------------------------

General information: TITO was launched using: RESULT: Template: 3H2T.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 360 11102 30.84 88.11 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain B : 0.59 3D Compatibility (PKB) : 30.84 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.345

(partial model without unconserved sides chains): PDB file : Tito_3H2T.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3H2T-query.scw PDB file : Tito_Scwrl_3H2T.pdb: