Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----MSSDHAHYWSVFFFVLILYAYHHGIFRSSTSLQAFIQQFGKYAVMIFVLLQVIQVIIPILPGG---------ISSVAGMLMFGNGFGLLYSCIGLVIGEAIGFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVAGLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL 1H6P Chain:A ((1-203)) AGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRPLGVSRLLRVMQCLSRIEEGENLSFDMEAELTPLESAINVLEMIKTEFT-----LTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMRNDLLNIIREKNLAHPV---------IQNFSYETFQQKMLRFLESHLDDAEPYLLTMAKKALK--

General information: TITO was launched using: RESULT: Template: 1H6P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 644 -29355 -45.58 -168.70 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -45.58 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.364

(partial model without unconserved sides chains): PDB file : Tito_1H6P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1H6P-query.scw PDB file : Tito_Scwrl_1H6P.pdb: