Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------------------MKPEYLIHAEHLTVILCPL----EKQHKILEHLKKEVLVA--------KLDNFAIIQKNWPMFPYLNLKDH-----------VLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKLQLLHALL--------------SKRNNIVIEDTFDEL----------SVLEIQELLHLLSYLAHEENQGILLFT-HDATIAQ-SPYIDRLEPAG---------- 2QV5 Chain:A ((3-248)) LGQLPVVGADGLRPMEQYARPWSGARGTRVAIVVGGLGLSQTGSQKAIRDLPPEVTLGFAASGNSLQRWMQDARREGHEILLQIPLEPFGYPGTNPGPDTLLAGDPAKVNIDRLHRSMAKITNYTGVMNYLGGRFLAEQSALEPVMRDIGKRGLLFLDDGSSAQSLSGGIAKAISAPQGFADVLLDGEVTEASILRKLDDLERIARRNGQAIGVASAFDESIAAISKWSREAGGRGIEIVGVSALV

General information: TITO was launched using: RESULT: Template: 2QV5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 817 11432 13.99 67.64 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : 13.99 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.333

(partial model without unconserved sides chains): PDB file : Tito_2QV5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QV5-query.scw PDB file : Tito_Scwrl_2QV5.pdb: