Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEELIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTIRGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF 1WKK Chain:B ((1-131)) MERTFVMIKPDGVRRGLVGEILARFERKGFRIAALKLM-QISQELAERHYAEHREKPFFPGLVRFITSGPVVAMVLEGPGVVAEVRKMMGATHPKDALPGTIRGDFATTID-----ENVIHGSATLEDAQREIALFF

General information: TITO was launched using: RESULT: Template: 1WKK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 596 -77058 -129.29 -588.23 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain B : 0.88 3D Compatibility (PKB) : -129.29 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.88 QMean score : 0.649

(partial model without unconserved sides chains): PDB file : Tito_1WKK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WKK-query.scw PDB file : Tito_Scwrl_1WKK.pdb: