Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSIITDVYAREILDSRGNPTIEVEVYTESG----------AFGRGMVPSGASTGEYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFN---TKVLPTPMMNIINGGSHADNSIDFQEFMIMPVGAPTFKEALRMGAEVFHALASILKAR--GLATSVGDEGGFAPNLGSNEEGFEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADS-------GEGEKTTDEMIKFYEELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK 3QTP Chain:B ((5-440)) SMSIQKVHAREILDSRGNPTIEVEITTGKGMFRSCVPSGASTGVHEAVELR-----------DGDKKRYGGKGVLKAVENVNTIIGPALLGKNVLNQAELDEMMIKLDGTNNKGKLGANAILGCSMSICRAAAAEKGLPLYKYLAELTGHKEMTMPVPCFNVINGGAHAGNALAMQEFMICPTGATNFHEALRMAAETYQCLKVVIKAKYGQDATNVGDEGGFAPNVSGAREALDLLVEAIAKAGY--TGKIEIAMDCAASEFYNEETKKYDLGKKIPADKKDPSLVKDVDGLIAEYVDYGKHYPIASIEDPFAEDDWAAWNKFTVEHG-NFQIVGDDLLVTNPARVQMAMDKNACNSVLIKVNQIGTLTETFKTIKMAQEKGWGVMASHRSGETEDTFIADLVVGLNCKQIKTGAPCRSERLCKYNQLMRIEEELGNI-PYAGK-NWRNST--

General information: TITO was launched using: RESULT: Template: 3QTP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2609 101116 38.76 244.24 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain B : 0.83 3D Compatibility (PKB) : 38.76 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.534

(partial model without unconserved sides chains): PDB file : Tito_3QTP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QTP-query.scw PDB file : Tito_Scwrl_3QTP.pdb: