Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAIRRIEGLLHLASEGRYAILVGRFNSFVVEHLLEGAIDTLKRHGVNEDNITVIHAPGAWELPIVAKKLATSNQFDAIIALGAVIRGSTPHFDFVAGECAKGLGVVALESSLPVINGVLTTDSIEQAIERSG--TKAGNKGSEAALTAIEMVNLLKAI 2C97 Chain:C ((15-139)) ------------ASGVRLAIVASSWHGKICDALLDGARKVAA--GCGLDDPTVVRVLGAIEIPVVAQELARNH--DAVVALGVVIRGQTPHFDYVCDAVTQGLTRVSLDSSTPIANGVLTTNTEEQALDRAGLPTSAEDKG-----------------

General information: TITO was launched using: RESULT: Template: 2C97.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 578 -95142 -164.60 -773.51 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain C : 0.77 3D Compatibility (PKB) : -164.60 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.599

(partial model without unconserved sides chains): PDB file : Tito_2C97.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2C97-query.scw PDB file : Tito_Scwrl_2C97.pdb: