Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDTNF--EDRNAFVTGIARYIEQATVH-SSMNEMLEE----GHEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMKFMYFQRKAIERFCSEVKRLCHAERRKDFVSEAYLLTLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNRITQCLHQQLEVIPGYEELLADIVNICVDYYENKMYLTPSEKHMLLKVMGFGLYLMDGNVSNIYKLDAKKRINLSKIDKFFKQLQVVPLFGDMQIELARYIKTSAHYEENKSKWTCTQSSIS--PQYNICEQMVQIR-DDHIRFISELARYSNSEVVTGSGLDSQKSDEEYRELFDLALRGLQLLSKWSAHVMEVYSWKLVHPTDKFCNKDCPGTAEEYERATRYNYTSEEKFAFVEVIAMIKG-----LQVLMGRMESVFNQAIRNTIYAALQDFAQVTLREPLRQAVRKKKNVLISVLQAIRKTICDWEGGREPPNDPCLRGEKDPKGGFDIKVPRRAVGPSSTQACQWSPRALFHPTGGTQGRRGCRSLLYMVRTMLESLIADKSGSKKTL-RSSLDGPIVLAIEDFHKQSFFFTHLLNISEALQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEPSMMEYVLYPLDLYNDSAYYALTKFKKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKAMAGSVLLDKRFRAECKNYGVIIPYPPSN-RYETLLKQRHVQLL-GRSIDLN-RLITQRISAAMYKSLDQAISRFESEDLTSIVELEWLLEINRLTHRLLCKHMTLDSFDAMFREANHNVSAPYGRITLHVFWELNFDFLPNYCYNGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIAYSHIYSSYRNFVGPPHFKTICRLLGYQGIAVVMEELLKIVKSLLQGTILQYVKTLIEVMPKICRLPRHEYGSPGILEFFHHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVCDLLHAAPFQNILPRVYIKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSYLQDPIWRGPPPTNGVMHVDEC--VEFHRLWSAMQFVYCIPVGTNEFTAEQCFGDGLNWAGCSIIVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVPLKKMADRIRKYQILNNEV--FAILNKYMKSVETDSSTVEHVRCFQPPIHQSLATTC- 4Q71 Chain:A ((3-990)) ----------------MPNIPPPFTAP-YAPDDAEIAARLLPASHLSPPQEARIHRTATRLIEAIRKRLGGVEDMLREFALSTKEGLALMVLAEALLRV---------PDARTADQFIEDKLGE-----GDFIHHETKSTAFLVNASAW--ARVIQPGETPDGTIGRLVKRLGAPAVRTATRQAMRLMGNHFVLGETIEQALERGKPGQKTRYSFDM---LGEGAR---TAADARRYFDAYASAIETIGK-------------AAGNHALPDRPGISVKLSALHPR--FEAISRARVMVELVPQLLDLAQRAKAH-DLNFTVDAEEADRLELSLDVIAATLADPSLKGWDGFGLAIQAYQKRASAVIDYVDALARAHDRKLMV-RLVKGAYWDTEIKRAQERGLDGYPVFTR--KAMTDLNYVACASKLLALRPRIFPQFA------------THNALTVATVLEMAEGSSGFEFQRLHGMGEALYEQLAKDHADIAYRTYAPVGSHRDLLAYLVRRLLENGANSSFVAQA-----ADYRVPVPALLQ-----RPADAIVRPQAAAHPRIPL-----PCDLFAPE-----RRNSRGVEFGARTALDQLLTDVKAEIADATPDQAHAAVAAARAGFAGWSR--TPAGIRAAALEQAAHLLESRSAHFIALLQREGGKT-----------------------LDDALSELREAADFCRYYAAQGRKLFGSE-------------------------TAMPGPTGESNALTMRGR--GVFVAISPWNFPLAIFLGQVTAALMAGNSVVAKPAEQTPRIAREAVALLHEAGI---PKSALYLVTGDGRIGAALTAHPDI-AGVVFTGSTEVARSINRALAAKDGPIV------------PLIAETGGINAMIADATAL---------------------PEQVADWVVTSAFRS-AGQRC--SALRLLFVQ--EDVADRMIEMVAGAAR---------------------------------------------ELKIGDPSDVA------------------------THVGPVID------VEAKQRLDAHIARMKTEARLHFAGPAPEGCFVAPHIFELTEAGQLTEEVF------------------------GP-----ILHVVRYRPENLERVLRAIER----------------TGYGLTLGVHSRI-----------------------DDSIEAIIDRVQV---GNIYVNRNMIGAVVGVQPFGGNGLSGTGPKAGGPHYLARFATEQTVTINTAAA

General information: TITO was launched using: RESULT: Template: 4Q71.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 5659 41520 7.34 43.80 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 7.34 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.212

(partial model without unconserved sides chains): PDB file : Tito_4Q71.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4Q71-query.scw PDB file : Tito_Scwrl_4Q71.pdb: