Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAFRQALQLAACGLAGGSAAVLFSAVAVGKPRAGGDAEPRPAEPPAWAGGARPGPGVWDPNWDRREPLSLINVRKRNVESGEEELASKLDHYKAKATRHIFLIRHSQYHVDG----SLEKDRTLTPLGREQAELTGLRLASLGLKFNKIVHSSMTRAIETTDIISRHLPG--VCKVSTDLLRE-------GAPIEPDPP-------------VS---------HW-----KPEAVQYYEDGARIEAAFRNYIHRADARQEEDSYEIFICHANVIRYIVCRALQFPPEGWLRLSLNNGSITHLVIRPNGRVALRTLGDTGFMPPDKITRS 3R7A Chain:B ((8-232)) -------------------------------------------------------------------------------------------ETDSNVVTLYVTRHGKTILNTNHRAQGWADSPLVEKGVEVATNLGTGLKD--IHFMNAYSSDSGRAIETANLVLKYSEQSKLKLEQRKKLRELNFGIFEGEKLDNMWDAVGKAAGVTSPEELLKFSIQEVIDLIRAADPTKQAEDWELFSTRIKAEIDKISEEAA--KDGGGNVLVVVHGLLITTLIEMLDSSK----TKLGVENASVTKIVYQD-GIYTVESVGDMSYVAKGK----

General information: TITO was launched using: RESULT: Template: 3R7A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 908 805 0.89 4.35 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain B : 0.64 3D Compatibility (PKB) : 0.89 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.487

(partial model without unconserved sides chains): PDB file : Tito_3R7A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3R7A-query.scw PDB file : Tito_Scwrl_3R7A.pdb: