Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELE-RVLSNERFRGRQRVLRDLRIVFKEFTIRTH 5WUR Chain:B ((19-156)) AFADIVDIYKDKIYQLCYRMLGNVHEAEDIAQEAFIRAYVNIDSFDI----NRKFSTWLYRIATNLTIDRIRKKKPDYYL---------------------------ELSNTIQQKILKLPDKYRTVIVLKYIDELSLI---------------------

General information: TITO was launched using: RESULT: Template: 5WUR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 319 -24008 -75.26 -224.37 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain B : 0.60 3D Compatibility (PKB) : -75.26 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.452

(partial model without unconserved sides chains): PDB file : Tito_5WUR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5WUR-query.scw PDB file : Tito_Scwrl_5WUR.pdb: