Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAVSTSTVIRKLREFKFETDWTKLPKVMSWDEYSFKKSKMSFIAQDFESKSILAILDGRTH---------------AVIRNHFQRYQREVRELVEVITM--------------DMYSPYYRLAK--QLFPK-----------AKIVLDRFHIVQHLSRAMNRVRIQIMNQFDRKSLEY-RALKRFWNPRFFVSRLGLNQSTGLIYYARIASSSVRNDSISPRFECT-- 3BOE Chain:A ((2-210)) --ISPAQIAEALQGRGWDAEIVT-------------DASMAGQLVDVRPEGILKCVDGRGSDNTRMGGPKMPGGIYAIAHNRGVTSIEGLKQITKEVASKGHLPSVHGDHSSDMLGCGFFKLWVTGRFDDMGYPRPQFDADQGANAVKDAGGIIEMHHGSHTEKVVYINLLANKTLEPNENDQRFIVDGWAADKFGLD----VPKFLIAAAATVEMLGGPKNAKIVVP

General information: TITO was launched using: RESULT: Template: 3BOE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 741 -19653 -26.52 -119.84 target 2D structure prediction score : 0.42 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -26.52 2D Compatibility (Sec. Struct. Predict.) : 0.42 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.158

(partial model without unconserved sides chains): PDB file : Tito_3BOE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3BOE-query.scw PDB file : Tito_Scwrl_3BOE.pdb: