Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEAQYKVLCVCLGNICRSPTAEVVFRHYCDQHQLN--IIVDSARTSNYHPNKAPDQRSQLHAKKRGYDLSSLRARQLSTQDFLDFDLILAMDHQNFDDIHDLLQRAIFQFGSHQIRAKVALMSEHDPQYPQQALPDPYYGGDEGFERVLDQCESSALAWINILKKQLNV 3JS5 Chain:A ((23-168)) -----KLLFVCLGNICRSPAAEAVMKKVIQNHHLTEKYICDSAGTCSYHEGQQADSRMRKVGKSRGYQVDSI-SRPVVSSDFKNFDYIFAMDNDNY---YELLDRC-----PEQYKQKIFKMVDFCTTIKTTEVPDPYYGGEKGFHRVIDILEDACENLI---------

General information: TITO was launched using: RESULT: Template: 3JS5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 790 22365 28.31 155.31 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : 28.31 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.356

(partial model without unconserved sides chains): PDB file : Tito_3JS5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3JS5-query.scw PDB file : Tito_Scwrl_3JS5.pdb: