Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MARNADYIDIAGFTIAPQ-TLLPYGHLYNASLA--GNQLNSAHGFAGPILAA-PIWLI--NKPERFFAIAPYLYVPIGTYHSDEALNI------------------DENRWKFDLQLGVFNNVAMIFLPKSRPMLFDMVHMMILLE--- 2NXP Chain:A ((8-156)) QPDVSAVLSAYNQQGDPTMYEEYYSGLKHFIECSLDCHRAELSQLFYPLFVHMYLELVYNQHENEAKSFFEKFHGDQECYYQDDLRVLSSLTKKEHMKGNETMLDFRTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEHLYIDIFD

General information: TITO was launched using: RESULT: Template: 2NXP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 421 -1578 -3.75 -12.93 target 2D structure prediction score : 0.43 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -3.75 2D Compatibility (Sec. Struct. Predict.) : 0.43 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.082

(partial model without unconserved sides chains): PDB file : Tito_2NXP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2NXP-query.scw PDB file : Tito_Scwrl_2NXP.pdb: