Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDKPVDVVHNCWGNLFNKNSQNKHIDEKIDYNKQSEHEDQRRENMNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAPENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSHLVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK 4FAK Chain:A ((2-163)) -----------------------------------------AEFMKITILAVGKLKEKYWKQAIAEYEKRLGPYTKIDIIEVPDEKAPENMSDKEIEQVKEKEGQRILAKIKPQSTVITLEIQGKMLSSEGLAQELNQRMTQGQSDFVFVIGGSNGLHKDVLQRSNYALSFSKMTFPHQMMRVVLIEQVYRAFKIMRGEAYHK

General information: TITO was launched using: RESULT: Template: 4FAK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 725 -101931 -140.59 -629.20 target 2D structure prediction score : 0.80 Monomeric hydrophicity matching model chain A : 0.86 3D Compatibility (PKB) : -140.59 2D Compatibility (Sec. Struct. Predict.) : 0.80 1D Compatibility (Hydrophobicity) : 0.86 QMean score : 0.726

(partial model without unconserved sides chains): PDB file : Tito_4FAK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4FAK-query.scw PDB file : Tito_Scwrl_4FAK.pdb: