Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRF--GNRVLKGIKIGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDY-LDDEVK-DMDPAIVIPQYFAQLSEALV-VIEADVFAHFDYGFRVFGLSVAE--FKQYEAQFLPILDQVIKNKLAFELNAKSAYLYDNLALYEYVIDLCLSRGGTLF 4GC3 Chain:A ((38-221)) CFTEHRDFYFPG--MDFSLNLPEYFQEINQLQAEFKDKIKIKIGLEMGIDLRFKSEINQFIDSAPFDFVIASVHEIGDIEVYDGTEFYLQKTKEEAQREYLLACLDVVQNFENYNSFGHLDYVARYGPYTDKSIKFAENREILFEILRALASKEKALEINTRLFDDPKTEQFYSDLLINFKRLGGK--

General information: TITO was launched using: RESULT: Template: 4GC3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 777 -21798 -28.05 -123.15 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -28.05 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.387

(partial model without unconserved sides chains): PDB file : Tito_4GC3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4GC3-query.scw PDB file : Tito_Scwrl_4GC3.pdb: