Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTIIYKRWLFMKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEVEPDLILLDLMLPKMDGLEVAREVRKT-YDMPIIMVTAKDSEIDKVLGLELGADDYVTKPFSNRELVARVKANLRR-GATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHREFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYLVTRRGVGYYLRNPEQE 1YS6 Chain:A ((30-231)) ---------------------------------SGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSAR--VDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTATSSSET-----ITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAG-GGPRLLHTVRGVGFVLR-----

General information: TITO was launched using: RESULT: Template: 1YS6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 939 -48196 -51.33 -243.41 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -51.33 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.624

(partial model without unconserved sides chains): PDB file : Tito_1YS6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YS6-query.scw PDB file : Tito_Scwrl_1YS6.pdb: