Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDKFVAFME-KHFIPVASKIGAQRHLVAIRD-SFMVSMPLMIL----GALAVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGY-RKDGVSAGVISLGSFFALGGALGMSSN-------GLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV-------PPAVAKAFASL------LPAMIT-------------ISAFALVAAIFAAFGVDDIVGSF-YTVVQEPFMGLANSYPSALLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVN-KPFFDSFVNLGGTGATLGLLLAIYL-VGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMFIPFILTPMVLVSVAYFATSTG------------LVP-AATVMPPWVTPPIIGG-VLATKSIAGGVLAAVNLVLSILIYL-PFVKVATIQERRKEALDA--------------------------------------------------- 4C0E Chain:A ((1674-2193)) LEAAHLLEQMEYVFDEWIHLCNNPHATERAAMIFVHQLHSVQLVTNRDEFLLFLRHALDKSVERFEQGIHSGAS----IAESFQAVEALVKLIIIFVKSHSAAVAFMD------SILALGVLVANSHHVKRGENFNQRVFYRFFALLLHEVGLLAGHFSKSHYEQIILNFAARLFDMRPNLLPGFACAWAGLVSHRAFLPVILGLPDEKGWAPFTKLLEQFLGCVGELVKTFTVSSLGKEMYHAALKILIVLQHDFP-IYLDKFRVQLCQSLPLHATQLVNLILAAIP-PNCNSLADPFQAGLKVDKIPDMKERPPTAFDSAGLLREAGLLDILERML--QNGP----SEDGVAQINHAINKSTSFGYVPLGVNRRLIDAVVARFAEFAINRASSRSDSAIFVAGANDIKTLQMLVTEVSPEARYYLVSSMVNELRYPNAYTNYFSQALLDIFGHDMSDPEENLVREQIVRVLLERVLGYWPQPWGLIITILELLKNDKYLFFELPFIKATPEVAERFTALARSAA

General information: TITO was launched using: RESULT: Template: 4C0E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 22 1341 60.93 3.36 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 60.93 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.435

(partial model without unconserved sides chains): PDB file : Tito_4C0E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4C0E-query.scw PDB file : Tito_Scwrl_4C0E.pdb: