Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVNEKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQISLNSEIPVMFGVLTTDTIEQAIERAG--TKAGNKGSECAQGAIEMVNLIRTLDA 2C97 Chain:B ((14-139)) --------DASGVRLAIVASSWHGKICDALLDGA--RKVAAGCGLDDPTVVRVLGAIEIPVVAQELARN--HDAVVALGVVIRGQTPHFDYVCDAVTQGLTRVSLDSSTPIANGVLTTNTEEQALDRAGLPTSAEDKG-------------------

General information: TITO was launched using: RESULT: Template: 2C97.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 581 -102272 -176.03 -824.77 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain B : 0.75 3D Compatibility (PKB) : -176.03 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.508

(partial model without unconserved sides chains): PDB file : Tito_2C97.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2C97-query.scw PDB file : Tito_Scwrl_2C97.pdb: