Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKIQIKQRP-L-LT--RPEQFQGVPPFIAEILARRGVQSEQELELKLKNLLA-PELKGLDAAVALMDQAIDEQKKIVIVGDYDADGATSTALMMLVLRDMGAQVDYLVPDRFKYGYGLTPAIAELAHHTYQPDLLITVDNGISSHAGVDAAHALGMQVIITDHHLTTKETPLAEAVVNPNQLGCEFPSKALAGVGVAFYVLANLASLRNRQGKSTSKVTQYLDLVALGTYADVAVLDYNNRILVDAGVKRIQQHQCRVGILALLDIAGREATSIRAQDLGFVLGPRINAAGRMESMRIGIECLLADTMETAYPIAQQLNQLNIDRRQIEGEMKQQALSALDSLQLSQQDIPAALVLFEENWHQGVIGIVAGRLKEQFHRPTIVFAPDEDGIHIKGSARSIDGVHIRDTIEQVAEQHPELVSHFGGHAAAAGLTIRKENFEAFKTVFNDCVA-AMDESIFQATLWTDGELPVSALQLDTLNWIEQLGPWGQKFPLPQFEGY-FKVIDFRWLKE-THLKLRLAIDQYSFDAIAFNAAGRFEFDPMRDHVHLVYEIDRNVFNGNVSLQLRIVHLNQ 2ZXO Chain:A ((3-528)) DRVRWRVLSLPPLAQWREVMAALEVGPEAALAYWHRGFRRKEDLDPP----LALLPLKGLREAAALLEEALRQGKRIRVHGDYDADGLTGTAILVRGLAALGADVHPFIP----------MERVPEHL--EASDLFLTVDCGITNHAELRELLENGVEVIVTDHHTPGKTPPPG-LVVHPALTPD--LKEKPTGAGVAFLLLWALHERLGL-----PPPLEYADLAAVGTIADVAPLWGWNRALVKEGLARIPASS-WVGLRLLAEAVGY---TGKAVEVAFRIAPRINAASRLGEAEKALRLLLTDDAAEAQALVGELHRLNARRQTLEEAMLRKLLPQAD-----P--EAKAIVLLDPEGHPGVMGIVASRILEATLRPVFLVAQ------GKGTVRSLAPISAVEALRSAE----DLLLRYGGHKEAAGFAMDEALFPAFKARVEAYAARFPDP--VREVALLDL-LPEPGLLPQVFRELALLEPYGEGNPEPLFLLFGAPE-EARRLGEGRHLAFRLK----GVRVLAWKQGDLA----LPPEVEVAGLLSENAWNGHLAYEVQAVDLR-

General information: TITO was launched using: RESULT: Template: 2ZXO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2809 21670 7.71 42.66 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : 7.71 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.396

(partial model without unconserved sides chains): PDB file : Tito_2ZXO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ZXO-query.scw PDB file : Tito_Scwrl_2ZXO.pdb: