Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMDYQNAVQAFDLESTAKQMLSGSLDALNACYECCDRHADG--DKIALYWQGKDGRKEQYTFRELKEWSSQFANFLKSQGVKAGDRISGLLPRTPELIVTILAAWRIGAVYQPLFTAFGPKAIEHRIQLAQSKLVVTDMGNR--SKLDEIE-KCPAIMTVADAQGTPLKAGDFNFWNEVKQQSDQCDL----VMRSIQDPFLLMFTSGTTGPAKPLE----VPLKALIAFGRYMQDAIGLTEEDSF-WNIADPGWAYGLYYAITGPLFLGHATLFYE-GGFSIDSLCQIVKDYKVNNLAGAPTAYRMMMAADPAQMAPLKGQFRVVSSAGEPLNPEVIRWFKQVLDAPIYDHYGQTEVGMVVCNHHGLKHEIHAGSAGFPSPGYRVAIVNEQGEELPPDTPGILAVDISQ-SPMMWFGGY-KESRKSPFIGH--YYLTGDTAELHADGSMSFVGRSDDVITTSGYRIGPFDVESALLEHDAVIEAAVIGVPDPDRTEVVKAFVILAAGIQPSDALAEELSQFVKRRLSAHAYPRLVEFVSELPKTPSGKIQRFLLRNQEIAKQQAKAG 3ETC Chain:A ((53-559)) -------------------------ENFNFAYDVVDVYARDSPEKLAMIWCDDYGNEKIFTFKDLKYYSDKAANFFVKHGIGKGDYVMLTLKSRYDFWYCMLGLHKLGAIAVPATHMLKTRDIVYRIEKAGLKMIVCIAEDDVPEQVDEAHAECGDIPLKKAKVGGDVLEGWIDFRKELEESSPIFERPTGEVSTKNEDICLVYFSSGTAGFPKMVEHDNTYPLGHILT-AKYWQNV----EDDGLHYTVADSGWGKCVWGKLYGQWIAGCAVFVYDYDRFEAKNMLEKASKYGVTTFCAPPTIYRFLIKEDL---NFSTLKYAVV--AGEPLNPEVFNRFLEFTGIKLMEGFGQTETVVTIATFPWM--EPKPGSIGKPTPGYKIELMDRDGRLCEVGEEGEIVINTMEGKPVGLFVHYGKDPERTEETWHDGYYHTGDMAWMDEDGYLWFVGRADDIIKTSGYKVGPFEVESALIQHPAVLECAITGVPDPVRGQVIKATIVLTKDYTPSDSLKNELQDHVKNVTAPYKYPRIIEFVPE---------------------------

General information: TITO was launched using: RESULT: Template: 3ETC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2790 12206 4.37 25.17 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : 4.37 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.506

(partial model without unconserved sides chains): PDB file : Tito_3ETC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ETC-query.scw PDB file : Tito_Scwrl_3ETC.pdb: