Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAAEEHALTSPEYIKHHLTNMTYGKMPDGTWKLAETAEEAHSMGFTAIHLDSMGWSIGLGVIFCLLFWIVARAANAGVPTKFQSAIEMIIEFVDSSVRDTFHGKSRLIAPLALTIFVWIFLMNLMDLIPVDWIPQVAAFVGANAFGMDPHHVYFKIVPSTDPNITLGMSLSVFVLILFYSIREKGVGGFVGELALNPFNPSNPVAKALLIPVNLILELVTFLARPISLALRLFGNMYAGELIFILIALLPFW----IQWALSVPWAIFHILVITLQAFIFMMLTIVYLSMASEKH 5LQZ Chain:Y ((119-250)) ------------------------------------------------------------------------------------------------------------------------------------------------------------------IYIIGISVSLWIGLTILGLFLNKA-VFFSLFV--PSGTP-----LPLVPVLVLIELLSYTARAISLGLRLAANTLSGHLLMSILGNLVK-IFGLIPLAGIFAIVILEFAIACIQAYVFAILTSSYLKDSIY--

General information: TITO was launched using: RESULT: Template: 5LQZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain Y - contact count / total energy / energy per contact / energy per residue : 213 -38535 -180.92 -326.57 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain Y : 0.58 3D Compatibility (PKB) : -180.92 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.031

(partial model without unconserved sides chains): PDB file : Tito_5LQZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5LQZ-query.scw PDB file : Tito_Scwrl_5LQZ.pdb: