Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIVILNKPYDVLSQFRKDEAHMTVSDFVDD---PTLRIAGRLDMDSEGLVFLTDHGGLNQFITNPANKKYKTYLVQVDGDVTEEALEQLRKGVELNDGM--TLPAKAIKVSEPEWLWDRDPPVRYRASIPTSWIEISICEGRNRQVRRMTSAVGFPTLRLIRTKIGTIDLVQLGLQPGETKEIEPLLYPDFKDVPAEQPYRSRSYVRKPGGTGGKPMVRKNKDGSAKKSGTKRIWQMDESEKPRRKTNGTTRPNTKAPRGRSRNSR 1VIO Chain:A ((62-233)) GQYFMLNKPQGCVCSND--D-YPTIYQFFDYPLAGKLHSAGRLDVDTTGLVLLTDDGQWSHRITSPKHHCEKTYLVTLADPVEENYSAACAEGILLRGEKEPTKPAK-------------LEIL------DDYNVNLTISEGRYHQVKRMFAALGNKVVGLHRWKIGDVVLDE-SLEEGEYRPLTQSEIEKLV--------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1VIO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 758 7273 9.59 44.08 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : 9.59 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.499

(partial model without unconserved sides chains): PDB file : Tito_1VIO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VIO-query.scw PDB file : Tito_Scwrl_1VIO.pdb: