Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRIYLMANFVLNAQARAEDKQGKGASRRLRRESLVPAIIYGGNAEPVTVTLELRELVKALESNAFFEKVVEIKVGDKVENVKIQALQRHPAKNTPMHADFKRA 1B75 Chain:A ((2-94)) --------FTINAEVRKE--QGKGASRRLRAANKFPAIIYGGKEAPLAIELDHDKVMNMQAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA

General information: TITO was launched using: RESULT: Template: 1B75.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 389 -48171 -123.83 -517.97 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -123.83 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.521

(partial model without unconserved sides chains): PDB file : Tito_1B75.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1B75-query.scw PDB file : Tito_Scwrl_1B75.pdb: