Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKT-NLNPNQMCEKLNTVLDN-NDSLFICELQKNYQG---R-ATEENWKFINEHIFS 3EXC Chain:X ((4-83)) --MKLLVVYDVSDD-SKRNKLANNLKKLG-LERIQRSAFEGDMD--RMKDLVRVVKLIVDTNTDIVHIIPLGIRDWERRIVIGR-------------

General information: TITO was launched using: RESULT: Template: 3EXC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain X - contact count / total energy / energy per contact / energy per residue : 257 -28089 -109.29 -390.12 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain X : 0.66 3D Compatibility (PKB) : -109.29 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.738

(partial model without unconserved sides chains): PDB file : Tito_3EXC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3EXC-query.scw PDB file : Tito_Scwrl_3EXC.pdb: