Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQGGNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQEL--SEVEANE-KLNADDLAGFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFEQEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIPRKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILLGTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNLISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL 2P0S Chain:B ((8-62)) -----------------------------------------------DMKTIAIADRTG-----EYEQLFKE--N----DEFRFVHAEKTAEEYRKMGADKSGIDAVLEIRQD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2P0S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 169 1596 9.44 30.69 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain B : 0.42 3D Compatibility (PKB) : 9.44 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.42 QMean score : 0.455

(partial model without unconserved sides chains): PDB file : Tito_2P0S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2P0S-query.scw PDB file : Tito_Scwrl_2P0S.pdb: