Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPGRSCVALVLLAAAVSCAVAQHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRWHELMLDKAPVLKVIVNSLKNMINTFVPSGKIMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTDIPLGEIISFNIFYELFTICTSIVAED---KKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPL--T---VNL-DFQRNNKTVFKASSF----AGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWILGKKDVMWIGFLTRTVLENSTSYEEAKNLLTKT----KILAPAYFILGGNQSGEGCVITRDRKESLDVYELDAKQGRWYVVQTNYDRWKHPF-----------------------------F------L----------DDRRTPAKMCLNRT----------------SQENISFETMYDVLSTK----P-----------VL------NKLTVYTTLIDVTKGQFETYLRDCPDPCIGW 5INR Chain:C ((9-329)) ----------------------------------------------------------------------------------------------------------------------------------------------CTSILVGKKASIDGSTLISRNDDGHEAL-D--PQRFVVVNPEDQPRDYTSVISKVNVKLPDDPQRYTSIPNSILTNGIWPA-AGINSSNVAMSATETITTNSRVQ--GLD-PFVENGLGEEDLVTVVLPYVKSAREGVKRLGSLLEEYGTYEPNGISFA-DN-EEVWWLETIGGHHWAAVRIP---DDAYVVAPNR--MNIDQFDFDSDDTLCSSDLKDLIDNNNLNPDFENYNLRHIFGSASIKDTVYNNPRTWYGQKFFSPDDTADDPMEQDLPFICHANRKISVEDVKFVLSSHFENTKYDVYGSGSQSDKTLFRPIGINRNHNVHILQIRN-----------------

General information: TITO was launched using: RESULT: Template: 5INR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1225 46968 38.34 211.57 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain C : 0.57 3D Compatibility (PKB) : 38.34 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.366

(partial model without unconserved sides chains): PDB file : Tito_5INR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5INR-query.scw PDB file : Tito_Scwrl_5INR.pdb: