Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WFHGAISREDAENLLESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFH 5DC0 Chain:B ((146-221)) WYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNT-LAELVHHH

General information: TITO was launched using: RESULT: Template: 5DC0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 259 -29667 -114.54 -395.55 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain B : 0.78 3D Compatibility (PKB) : -114.54 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.554

(partial model without unconserved sides chains): PDB file : Tito_5DC0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DC0-query.scw PDB file : Tito_Scwrl_5DC0.pdb: