Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEVVMDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGRKVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD-- 2KYZ Chain:A ((1-67)) MRYVLY------VPDISCNHCKMRISKALEELGVKNYEVSVEEKKVVVETE----------NLDSVLKKLEEIDYPVESYQEV

General information: TITO was launched using: RESULT: Template: 2KYZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 251 -46240 -184.22 -711.38 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -184.22 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.464

(partial model without unconserved sides chains): PDB file : Tito_2KYZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2KYZ-query.scw PDB file : Tito_Scwrl_2KYZ.pdb: