Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEFLLYTISKVKLLEDILMPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLEMVEQL--LDKVLLYDNSSI 1UW1 Chain:A ((9-75)) ------DDKKTNWLKRIYRVRPCVKCKVA---PRNWKVKNK---HLRIYNMCKTCFNNSIDIGDDTYHGHDDWLMYADS--

General information: TITO was launched using: RESULT: Template: 1UW1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 201 -14951 -74.38 -230.02 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -74.38 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.363

(partial model without unconserved sides chains): PDB file : Tito_1UW1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1UW1-query.scw PDB file : Tito_Scwrl_1UW1.pdb: