Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---MVEQIPVGHNSGSFFLFLLLRLLLSPLLRNSISFLTSQGIPWKLSNNK-TKPIDKPTASKSIATNPLLLHLR 4KSN Chain:A ((8-72)) DTHLADLYLLKYDTG----LGVYESFICKYLEDSNDYIASH--PQKLSLDEMPRPLESETVSLRQLIVSVL----

General information: TITO was launched using: RESULT: Template: 4KSN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 136 4284 31.50 70.23 target 2D structure prediction score : 0.31 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : 31.50 2D Compatibility (Sec. Struct. Predict.) : 0.31 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.026

(partial model without unconserved sides chains): PDB file : Tito_4KSN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4KSN-query.scw PDB file : Tito_Scwrl_4KSN.pdb: