Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLIYKVYLNIISLHWGRTDMNLSYLKTSLYTAATTAILLCSSQSQAQQYYKWMDKSGS---THYTTTPP------PKGAKHLNKVSTYGSQPLLKNPTSNSEQPSQDKDKVVQEVTNVAVEKGAPAVPVPPAPSVSAPR 1K6Q Chain:H ((74-143)) -----------------TSSNTAYLQLSSLTSEDTAVYYCARDTAA--YFDYWGQGTTLTVSSAKTTPPSVYPLAPGSA---NSMVTLG--------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1K6Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain H - contact count / total energy / energy per contact / energy per residue : 75 -4478 -59.71 -77.21 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain H : 0.64 3D Compatibility (PKB) : -59.71 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.219

(partial model without unconserved sides chains): PDB file : Tito_1K6Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1K6Q-query.scw PDB file : Tito_Scwrl_1K6Q.pdb: