Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLKQTLLYTGKAKSVYETDNADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEKLAEAGIETHFEKLLSPTEVLVKKLQMIPVECVIRNYAAGSLCRRLGVEEGKELTPPTFELFYKDDGLGDPMVNESQAIALGWATAEQLEQMKVLTYKVNDVLKALFAEGNMILVDFKLEFGVFHDR---IVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGVDLSDI 4O7W Chain:A ((7-231)) ------VYEGKAKKMIPIDD-DKLIMEFKDDATAFDGTKKARFKGKGWLNAQLSVIFFKLLEEHGIKTHFIGVAGGNRLIVEKLDMYPLEVVVRNVVAGSLKKRLPLPEGYELPEPIVELYYKNDELHDPMINYYHAKVLG-ISLDEIKKIEEIALKVNEILKDYLAKKGIILVDFKLEFG--KDKNGDIVLADEISPDTCRFWDAKTKRSLDKDVFRFDKGDLIEAYKEIYERI-------

General information: TITO was launched using: RESULT: Template: 4O7W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1072 -45952 -42.87 -206.99 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -42.87 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.527

(partial model without unconserved sides chains): PDB file : Tito_4O7W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4O7W-query.scw PDB file : Tito_Scwrl_4O7W.pdb: