Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERMKKSLVKLVGE--EAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGN-VSDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAKASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVTIEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS 5CG2 Chain:A ((45-297)) -GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIR-----------------EAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIA

General information: TITO was launched using: RESULT: Template: 5CG2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1274 -82398 -64.68 -353.64 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.86 3D Compatibility (PKB) : -64.68 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.86 QMean score : 0.538

(partial model without unconserved sides chains): PDB file : Tito_5CG2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5CG2-query.scw PDB file : Tito_Scwrl_5CG2.pdb: