Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQIIDDVAGVTLASASTLDKEISG----GTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHGRVQALAEAARENGLEF 1ILY Chain:A ((22-111)) ---------------------------RLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLALK---LKGN--KTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAREGGLEF

General information: TITO was launched using: RESULT: Template: 1ILY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 428 -18316 -42.79 -212.97 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -42.79 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.384

(partial model without unconserved sides chains): PDB file : Tito_1ILY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ILY-query.scw PDB file : Tito_Scwrl_1ILY.pdb: