Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNTSTAKHNYAPDILGAGYEQLTLNFPDDYEGKVVATLVRKKATQPTQKAVLYIHGFLDYFFQTE-MAEQFNAHGYDFYALDLRKYGRSKLPHQIFYNVLDLIEYDAEITQALEIIGQEKHTQVLLAGHSTGGLTATLYAAHHPDHPLIKALWA-NSPFYDFNLSLVEKKFGIPMLSRVGKYLPKVKFPSQLNKWYTTSLHKQLKGEWDFNLDWKPTSAPTVQLSFVHAIHTAQKEIHRGVKLNIPALIMHSHQTKNPRKWGPDATQSDVILDVKDIAKFGKKMKGDVSVVSIHNGLHDLVLSAQPVREQVYQQLFQWLDQKVT 1ZD3 Chain:A ((260-366)) -------------------------------------------------AVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVL--CKEMVTFLDKLG---LSQAVFIGHDWGGMLVWYMALFYPER--VRAVASLNTPFIPAN-----------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1ZD3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 473 -40782 -86.22 -388.40 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -86.22 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.483

(partial model without unconserved sides chains): PDB file : Tito_1ZD3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ZD3-query.scw PDB file : Tito_Scwrl_1ZD3.pdb: