Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFTRTVQTLK---NSTDLVQRF-ALPEIWEDFELRRLSNKDRYKHYILIFKNVVSQKKDWEDVKVVAEIQERNHNLRFNIKISKQYPELAAYEKLLEAKINAIINQSSLVIS 3WIH Chain:A ((1-96)) APPQGVTVSKNDGNGTAILVSWQPPPEMVQEYKVWCLGNETRYH---------INKTVDGSTFSVV--IPFLVPGIRYSVEVAASGSGVKSEPQFIQLD-------------

General information: TITO was launched using: RESULT: Template: 3WIH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 355 20700 58.31 246.43 target 2D structure prediction score : 0.30 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : 58.31 2D Compatibility (Sec. Struct. Predict.) : 0.30 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.032

(partial model without unconserved sides chains): PDB file : Tito_3WIH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3WIH-query.scw PDB file : Tito_Scwrl_3WIH.pdb: