Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRVIVLGSGVIGVASAYYLARQGAEVTVLDRQSGPAEETSFGNAGQISPGYSTPWAAPGIPFKAVKWMFQHHAPLAINLDGSMWQLQWMAQMLKNCNPQSYAVNKERMMRVAEYSRDCLRELRKDTGIHYENRAKGTLQLFRKEAQMEAVQRDISVLEECGVSYELLNGNELGRVEPALANAQDKLVGGLHLPNDETGDCYLFTNALAQIAKELGVNFQFNQNVEKLIVEGDQIKGVQVNGKVLTADRYVLAFGSYSRDFLKPLDLQLPVYP---VKGY------SLTIPIVAPAFAPQSTVLDETY-----------KIAITRFDQRIRVGGMAELSGFNLGLNEDRHATLQMVTQDLFPGGDMEQASFWTGLRPMTPDSTPIIG-ATRFKNLFLNTGHGTLGWTMACGSGKLISDIVLNHKTDISTDGLSIQRYSHAHAA 1EL5 Chain:A ((6-377)) --VIVVGAGSMGMAAGYQLAKQGVKTLLVDAFDPPHTNGS------------------------------HHGDTRIIR-------------------HAYGEGRE-YVPLALRSQELWYELEKET--HHKIFTKTGVLVFGPKGESAFVAETMEAAKEHSLTVDLLEGDEINKRWPGITVPEN--YNAIFEPNSGVLFSENCIRAYRELAEARGAKVLTHTRVEDFDISPDSVKIETANGS-YTADKLIVSMGAWNSKLLSKLNLDIPLQPYRQVVGFFESDESKYSNDIDFPGFMVE--VPNGIYYGFPSFGGCGLKLGYHTFGQKIDPDTINR----EFGVYPEDESNLRAFLEEYMPGANGELKRGAVCMYTKTLDEHFIIDLHPEHSNVVIAAGFSGHGFKFSSGVGEVLSQLALTGKTEHDISIFSINR-------

General information: TITO was launched using: RESULT: Template: 1EL5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2195 -112118 -51.08 -319.42 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -51.08 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.435

(partial model without unconserved sides chains): PDB file : Tito_1EL5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1EL5-query.scw PDB file : Tito_Scwrl_1EL5.pdb: