Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVFRSGL--LLACAAVFLQIAVFLQPLL-PKQYQIAPVCETITRALL-K---------PKAQTEAMSHAMHHTHHQHHIEQ---------------------------AQVPDHHDHHDANHQCQYCTVYANLVLPPEF----GVKEVLVRIQVRLVAYQQAFRHVYFALQRLFLLPQG----RAPPLFA--------------------- 4RD8 Chain:A ((9-218)) NPIKRALQGELLQNEPFIQLCTKIENYLMD-TEAVNEQLIELNEQLTMRLKEKGLKPGEKGATKQLRTLIQEILTEAGFREGMLQTIGNKPLAAADFMFLVSSGFMLKDSSLRASSHGELTHAIQWCLIILKRKKDSSFLENIPTSEICDRIYKKLGHQDSSNPNYPFTCWDVLIDKLGEIDSRSPEWLSDHIQNDEDQIFPVLREVIKNR

General information: TITO was launched using: RESULT: Template: 4RD8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1 46 45.50 0.32 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 45.50 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.62 QMean score : ?

(partial model without unconserved sides chains): PDB file : Tito_4RD8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4RD8-query.scw PDB file : Tito_Scwrl_4RD8.pdb: