Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYHA-SKLSIDEEVYFENLMQLVEHY 5DC0 Chain:B ((146-221)) WYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHH

General information: TITO was launched using: RESULT: Template: 5DC0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 259 -29026 -112.07 -387.01 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain B : 0.79 3D Compatibility (PKB) : -112.07 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.651

(partial model without unconserved sides chains): PDB file : Tito_5DC0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DC0-query.scw PDB file : Tito_Scwrl_5DC0.pdb: