Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTALVVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVD-LASHYHFSMLAKNAKDMAAGAVLVVSLFAALTGALIFLPRIWDLLF 5D6I Chain:A ((19-125)) --------------IIKAAGYSWKGLRAAWINEAAFRQEGVAVLLAVVIACWLDVDACTRVLLISSVMLVMIVELLNSAIEAVVDRIGSEYH--ELSGRAKDLGSAAVLIAIIDAVITWCILL---------

General information: TITO was launched using: RESULT: Template: 5D6I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 251 -35988 -143.38 -339.50 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -143.38 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.304

(partial model without unconserved sides chains): PDB file : Tito_5D6I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5D6I-query.scw PDB file : Tito_Scwrl_5D6I.pdb: