Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIVKFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSIKTKFDKIAPILQTIHTSAKELRGEFAPFEE------------IKKYESLIEEQIPYAN---YESVRNAVFSLEKRLADLGVDRKSCHIDLVPEN--FIESPQG-RLYLIDWEYSSMNDPMWDLAALFLE-----------------SEFTSQEEET-FLSHYESDQT---PVSHE-----------KIAIYKILQDTIWSLWTVYKEEQGE-DFG--DYGVNRYQRAVKGLASYGGSDEK 3LQ3 Chain:A ((154-385)) ------------------------------------------------------------------------------------------------IPSRPLKTQELREPVLSAAIATKMAQFHGMEMPFTKEPHWLFGTMERYLKQIQDLPPTGLPEMNLLEMYSLKDEMGNLRKLLESTPSPVVFCHNDIQEGNILLLSEP--DSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKARPTDYPTQEQQLHFIRHYLAEAKKGETLSQEEQRKLEEDLLVEVSRYALASHFFWGLWSILQASMSTIEFGYLDYAQSRFQ---------------

General information: TITO was launched using: RESULT: Template: 3LQ3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 585 14480 24.75 82.27 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 24.75 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.504

(partial model without unconserved sides chains): PDB file : Tito_3LQ3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3LQ3-query.scw PDB file : Tito_Scwrl_3LQ3.pdb: