Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKRIIPVYIFQQVNVLLVS------LYLL---------KFLCI-----GELTILQIL------YGSSLISFLWMYGQRKQA---HKVNMKSRMKWLGVEFVSLLII----SLCFSLIHAQGSTNQANLIGLQHQIPWFSFLLFLIN------------------ASMVEEFLYREILCNLVRKLDIRVALTSVLFALAHHTGTILAW----CLYVSL-GMFLGMVRYKSDLWGSMGLH--LVWNLL---VYSLLLF-------- 1FZC Chain:B ((67-325)) -SCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGG---GWWYNRCHAANPNGRYYWGGQYTWDMA-KHGTDDGVVWMNWKGSWYSMRKMSMKIRPFF

General information: TITO was launched using: RESULT: Template: 1FZC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 801 -26216 -32.73 -137.98 target 2D structure prediction score : 0.19 Monomeric hydrophicity matching model chain B : 0.61 3D Compatibility (PKB) : -32.73 2D Compatibility (Sec. Struct. Predict.) : 0.19 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.044

(partial model without unconserved sides chains): PDB file : Tito_1FZC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1FZC-query.scw PDB file : Tito_Scwrl_1FZC.pdb: